BDBM330211 3-Chloro-N-[4-[(1R,4S)-5-oxa-2-azabicyclo[2.2.1]heptan-4-yl]phenyl]benzamide::US9663530, Example 55

SMILES: Clc1cccc(c1)C(=O)Nc1ccc(cc1)[C@@]12CN[C@@H](CO1)C2

InChI Key: InChIKey=DOMSROAYECYWHA-SJLPKXTDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (TAAR1) (Rattus norvegicus (Rat))	BDBM330211 (3-Chloro-N-[4-[(1R,4S)-5-oxa-2-azabicyclo[2.2.1]he...) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(cc1)[C@@]12CN[C@@H](CO1)C2 |r| Show InChI InChI=1S/C18H17ClN2O2/c19-14-3-1-2-12(8-14)17(22)21-15-6-4-13(5-7-15)18-9-16(10-23-18)20-11-18/h1-8,16,20H,9-11H2,(H,21,22)/t16-,18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	964	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse))	BDBM330211 (3-Chloro-N-[4-[(1R,4S)-5-oxa-2-azabicyclo[2.2.1]he...) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(cc1)[C@@]12CN[C@@H](CO1)C2 |r| Show InChI InChI=1S/C18H17ClN2O2/c19-14-3-1-2-12(8-14)17(22)21-15-6-4-13(5-7-15)18-9-16(10-23-18)20-11-18/h1-8,16,20H,9-11H2,(H,21,22)/t16-,18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair