BDBM332621 3-(4-chlorophenyl)-1-{2-[(4-chlorophenyl)carbonyl]-2,7-diazaspiro[3.5]non-7-yl}prop-2-yn-1-one::US10196369, Compound C76

SMILES: Clc1ccc(cc1)C#CC(=O)N1CCC2(CN(C2)C(=O)c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=IJVUEFTWHNOACC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332621 (3-(4-chlorophenyl)-1-{2-[(4-chlorophenyl)carbonyl]...) Show SMILES Clc1ccc(cc1)C#CC(=O)N1CCC2(CN(C2)C(=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C23H20Cl2N2O2/c24-19-6-1-17(2-7-19)3-10-21(28)26-13-11-23(12-14-26)15-27(16-23)22(29)18-4-8-20(25)9-5-18/h1-2,4-9H,11-16H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair