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SMILES: COCCCOc1cc(cc(F)c1F)N1CCc2nc(ncc2C1)-c1ccccn1

InChI Key: InChIKey=XUFLAFNAKKJMJD-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333019   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis GB virus B)		BDBM333019
PNG
(US10196391, Example 19)
Show SMILES COCCCOc1cc(cc(F)c1F)N1CCc2nc(ncc2C1)-c1ccccn1
Show InChI InChI=1S/C22H22F2N4O2/c1-29-9-4-10-30-20-12-16(11-17(23)21(20)24)28-8-6-18-15(14-28)13-26-22(27-18)19-5-2-3-7-25-19/h2-3,5,7,11-13H,4,6,8-10,14H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 461n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...

US Patent US10196391 (2019)


BindingDB Entry DOI: 10.7270/Q2XK8HNM
More data for this
Ligand-Target Pair