BDBM333106 US10196391, Example 106
SMILES: COCCCNC(=O)c1cc(F)cc(c1)N1CCc2nc(ncc2C1)-c1ncccn1
InChI Key: InChIKey=WHXBADLYTUTWRK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatitis GB virus B NS5B RNA-dependent RNA polymerase (Hepatitis GB virus B) | BDBM333106 (US10196391, Example 106) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ... | US Patent US10196391 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HNM | |||||||||||
More data for this Ligand-Target Pair |