BDBM333381 N-(2-{[3-(1-Benzofuran-2- yl)imidazo[1,2-b]pyridazin- 6-yl]oxy}ethyl)propan-1- amine::US9730929, Example 2

SMILES: CCCN(CCO)c1ccc2ncc(-c3cc4ccccc4o3)n2n1

InChI Key: InChIKey=IEQRQIVSJPSTCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM333381 (N-(2-{[3-(1-Benzofuran-2- yl)imidazo[1,2-b]pyridaz...) Show SMILES CCCN(CCO)c1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C19H20N4O2/c1-2-9-22(10-11-24)19-8-7-18-20-13-15(23(18)21-19)17-12-14-5-3-4-6-16(14)25-17/h3-8,12-13,24H,2,9-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...				US Patent US9730929 (2017) BindingDB Entry DOI: 10.7270/Q28S4S1H
					More data for this Ligand-Target Pair