BDBM336523 1-(5-(4-ethyl-5- fluoropyridin-3-yl)- 6-fluoroindolin-1- yl)ethanone::US9745282, 49

SMILES: CCc1c(F)cncc1-c1cc2CCN(C(C)=O)c2cc1F

InChI Key: InChIKey=CUXIZWXSADOSKO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM336523 (1-(5-(4-ethyl-5- fluoropyridin-3-yl)- 6-fluoroindo...) Show SMILES CCc1c(F)cncc1-c1cc2CCN(C(C)=O)c2cc1F Show InChI InChI=1S/C17H16F2N2O/c1-3-12-14(8-20-9-16(12)19)13-6-11-4-5-21(10(2)22)17(11)7-15(13)18/h6-9H,3-5H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent									US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM336523 (1-(5-(4-ethyl-5- fluoropyridin-3-yl)- 6-fluoroindo...) Show SMILES CCc1c(F)cncc1-c1cc2CCN(C(C)=O)c2cc1F Show InChI InChI=1S/C17H16F2N2O/c1-3-12-14(8-20-9-16(12)19)13-6-11-4-5-21(10(2)22)17(11)7-15(13)18/h6-9H,3-5H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair