BDBM338957 US10201527, Compound 52::US10736881, Compound 52

SMILES: Cn1c(CCCc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12

InChI Key: InChIKey=VNWZCFZHQXQJIB-ACCUITESSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM338957 (US10201527, Compound 52 | US10736881, Compound 52) Show SMILES Cn1c(CCCc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C20H21N3O2/c1-23-18-12-10-16(11-13-20(24)22-25)14-17(18)21-19(23)9-5-8-15-6-3-2-4-7-15/h2-4,6-7,10-14,25H,5,8-9H2,1H3,(H,22,24)/b13-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
MEI Pharma, Inc. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10736881 (2020)
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM338957 (US10201527, Compound 52 | US10736881, Compound 52) Show SMILES Cn1c(CCCc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C20H21N3O2/c1-23-18-12-10-16(11-13-20(24)22-25)14-17(18)21-19(23)9-5-8-15-6-3-2-4-7-15/h2-4,6-7,10-14,25H,5,8-9H2,1H3,(H,22,24)/b13-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
MEI PHARMA, INC. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10201527 (2019) BindingDB Entry DOI: 10.7270/Q2PK0J7F
					More data for this Ligand-Target Pair