null
SMILES: COc1nc2ccc(cc2c(Cl)c1CC1CCOCC1)[C@@](O)(C1CCN(CC1)C(C)=O)c1cncn1C
InChI Key: InChIKey=ISCFYYWYFSKXCV-NDEPHWFRSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM339034 (US10201546, Example 5b) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description For the RORγt construct used in the ThermoFluorŪ assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR... | US Patent US10201546 (2019) BindingDB Entry DOI: 10.7270/Q2F47R8C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM339034 (US10201546, Example 5b) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (... | US Patent US10201546 (2019) BindingDB Entry DOI: 10.7270/Q2F47R8C | |||||||||||
More data for this Ligand-Target Pair |