BDBM340345 US9758538, Example 33
SMILES: CS(=O)(=O)N1CC[C@@](CO)(C1)Nc1cc(nc(n1)N1CCOCC1)-c1cnc(N)nc1
InChI Key: InChIKey=QBDMEXDBIHVBTA-SFHVURJKSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PI3-kinase class I (Homo sapiens (Human)) | BDBM340345 (US9758538, Example 33) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
PFIZER INC. US Patent | Assay Description The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85... | US Patent US9758538 (2017) BindingDB Entry DOI: 10.7270/Q27D2X70 | |||||||||||
More data for this Ligand-Target Pair |