BDBM34102 benzamide derivative 15b
SMILES: COc1cccc(NC(=O)c2cccc(c2)C(=O)Nc2cccc(OC)c2)c1
InChI Key: InChIKey=KSLPIXQLWACJBY-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human)) | BDBM34102 (benzamide derivative 15b) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institutes for Biological Sciences | Assay Description The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph... | Bioorg Med Chem 17: 7301-12 (2009) Article DOI: 10.1016/j.bmc.2009.08.045 BindingDB Entry DOI: 10.7270/Q2DF6PK0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen Phosphorylase (PYGM) (Oryctolagus cuniculus (rabbit)) | BDBM34102 (benzamide derivative 15b) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institutes for Biological Sciences | Assay Description The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct... | Bioorg Med Chem 17: 7301-12 (2009) Article DOI: 10.1016/j.bmc.2009.08.045 BindingDB Entry DOI: 10.7270/Q2DF6PK0 | |||||||||||
More data for this Ligand-Target Pair |