BDBM345892 US10202367, Compound 38

SMILES: COc1cccc(F)c1C1=NC(CN2CCC(CC2)C(=O)NCCCN2C[C@@H](C)C[C@@H](C)C2)C(C)O1

InChI Key: InChIKey=FNJSYNCSLKFAEE-SQUILIJDSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 2a (isolate HC-J6) (HCV...)	BDBM345892 (US10202367, Compound 38) Show SMILES COc1cccc(F)c1C1=NC(CN2CCC(CC2)C(=O)NCCCN2C[C@@H](C)C[C@@H](C)C2)C(C)O1 |r,t:10| Show InChI InChI=1S/C28H43FN4O3/c1-19-15-20(2)17-33(16-19)12-6-11-30-27(34)22-9-13-32(14-10-22)18-24-21(3)36-28(31-24)26-23(29)7-5-8-25(26)35-4/h5,7-8,19-22,24H,6,9-18H2,1-4H3,(H,30,34)/t19-,20+,21?,24?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	455	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Kansas US Patent					Assay Description This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...				US Patent US10202367 (2019) BindingDB Entry DOI: 10.7270/Q23B6277
					More data for this Ligand-Target Pair