BDBM346225 US10202373, Compound I-39::US10202373, Example 3D

SMILES: CC(=O)Nc1cc(ccn1)-c1cncc2n(ccc12)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=GTLGRORLAZKGBO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM346225 (US10202373, Compound I-39 | US10202373, Example 3D) Show SMILES CC(=O)Nc1cc(ccn1)-c1cncc2n(ccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H16N4O3S/c1-14(25)23-20-11-15(7-9-22-20)18-12-21-13-19-17(18)8-10-24(19)28(26,27)16-5-3-2-4-6-16/h2-13H,1H3,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
MILLENNIUM PHARMACEUTICALS, INC. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US10202373 (2019) BindingDB Entry DOI: 10.7270/Q2FN18BC
					More data for this Ligand-Target Pair