BDBM346977 US10202379, Reference Example 712

SMILES: C[C@@H](N1CN([C@H]2c3ccccc3CSc3ccccc23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F

InChI Key: InChIKey=XUMGCXDMHKYUSO-VLIAUNLRSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346977 (US10202379, Reference Example 712) Show SMILES C[C@@H](N1CN([C@H]2c3ccccc3CSc3ccccc23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C25H22F3N3O4S/c1-14(25(26,27)28)29-13-31(30-10-16(11-32)22(33)23(34)21(30)24(29)35)20-17-7-3-2-6-15(17)12-36-19-9-5-4-8-18(19)20/h2-10,14,20,32,34H,11-13H2,1H3/t14-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.45	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346977 (US10202379, Reference Example 712) Show SMILES C[C@@H](N1CN([C@H]2c3ccccc3CSc3ccccc23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C25H22F3N3O4S/c1-14(25(26,27)28)29-13-31(30-10-16(11-32)22(33)23(34)21(30)24(29)35)20-17-7-3-2-6-15(17)12-36-19-9-5-4-8-18(19)20/h2-10,14,20,32,34H,11-13H2,1H3/t14-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.4	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair