BDBM347123 2-(4-((4-isopropylphenyl) (piperidin-3-yl)amino)phenoxy) pyrido[3,4-d]pyrimidin-4-ol::US10202381, Example 130::US10208039, Example 130

SMILES: CC(C)c1ccc(cc1)N(C1CCCNC1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1

InChI Key: InChIKey=OTAMOTHWTAFGQO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347123   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM347123 (2-(4-((4-isopropylphenyl) (piperidin-3-yl)amino)ph...) Show SMILES CC(C)c1ccc(cc1)N(C1CCCNC1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H29N5O2/c1-18(2)19-5-7-20(8-6-19)32(22-4-3-14-28-16-22)21-9-11-23(12-10-21)34-27-30-25-17-29-15-13-24(25)26(33)31-27/h5-13,15,17-18,22,28H,3-4,14,16H2,1-2H3,(H,30,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM347123 (2-(4-((4-isopropylphenyl) (piperidin-3-yl)amino)ph...) Show SMILES CC(C)c1ccc(cc1)N(C1CCCNC1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H29N5O2/c1-18(2)19-5-7-20(8-6-19)32(22-4-3-14-28-16-22)21-9-11-23(12-10-21)34-27-30-25-17-29-15-13-24(25)26(33)31-27/h5-13,15,17-18,22,28H,3-4,14,16H2,1-2H3,(H,30,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair