BDBM347138 2-(4-((2-methoxy-5-(4-methylpiperazin-1-yl) phenyl)(methyl)amino)phenoxy) pyrido[3,4-d]pyrimidin-4-ol::US10202381, Example 145
SMILES: COc1ccc(cc1N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1C)N1CCN(C)CC1
InChI Key: InChIKey=AEUHSMWQCJHBGF-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM347138![]() (2-(4-((2-methoxy-5-(4-methylpiperazin-1-yl) phenyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
CELGENE QUANTICEL RESEARCH, INC. US Patent | Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ... | US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM | |||||||||||
More data for this Ligand-Target Pair |