BDBM347381 US10869871, ID # SW208432::US9789116, SW208432

SMILES: CCCCS(=O)c1cc2ccc(nc2s1)-c1ccccc1

InChI Key: InChIKey=IKHGZAZIJAGYNY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM347381 (US10869871, ID # SW208432 | US9789116, SW208432) Show SMILES CCCCS(=O)c1cc2ccc(nc2s1)-c1ccccc1 Show InChI InChI=1S/C17H17NOS2/c1-2-3-11-21(19)16-12-14-9-10-15(18-17(14)20-16)13-7-5-4-6-8-13/h4-10,12H,2-3,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.53	n/a	n/a	n/a	n/a	n/a	n/a
CASE WESTERN RESERVE UNIVERSITY; THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM US Patent					Assay Description Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...				US Patent US10869871 (2020)
					More data for this Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM347381 (US10869871, ID # SW208432 | US9789116, SW208432) Show SMILES CCCCS(=O)c1cc2ccc(nc2s1)-c1ccccc1 Show InChI InChI=1S/C17H17NOS2/c1-2-3-11-21(19)16-12-14-9-10-15(18-17(14)20-16)13-7-5-4-6-8-13/h4-10,12H,2-3,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.53	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University; Board of Regents of the University of Texas System US Patent					Assay Description Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay.				US Patent US9789116 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34T5
					More data for this Ligand-Target Pair