BDBM347547 2-(Azetidin-1-yl)-4-{[3-(4-chloro-2-methylphenyl)piperidin-1-yl]carbonyl}pyridine::US9790201, 33

SMILES: Cc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1ccnc(c1)N1CCC1

InChI Key: InChIKey=GTUAUFCLACUKJD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347547 (2-(Azetidin-1-yl)-4-{[3-(4-chloro-2-methylphenyl)p...) Show SMILES Cc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1ccnc(c1)N1CCC1 Show InChI InChI=1S/C21H24ClN3O/c1-15-12-18(22)5-6-19(15)17-4-2-9-25(14-17)21(26)16-7-8-23-20(13-16)24-10-3-11-24/h5-8,12-13,17H,2-4,9-11,14H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair