BDBM347561 4-{[3-(4-Methoxyphenyl)piperidin-1-yl]carbonyl}-N,N-dimethylpyridin-2-amine::US9790201, 47

SMILES: COc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N(C)C

InChI Key: InChIKey=HGZOGADEWDVYQA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347561 (4-{[3-(4-Methoxyphenyl)piperidin-1-yl]carbonyl}-N,...) Show SMILES COc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N(C)C Show InChI InChI=1S/C20H25N3O2/c1-22(2)19-13-16(10-11-21-19)20(24)23-12-4-5-17(14-23)15-6-8-18(25-3)9-7-15/h6-11,13,17H,4-5,12,14H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair