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SMILES: FC(F)(F)c1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnnc(c1)N1CCC1

InChI Key: InChIKey=NYONQNORSBQLBF-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347592   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM347592
PNG
(3-(Azetidin-1-yl)-5-({3-[4-chloro-2-(trifluorometh...)
Show SMILES FC(F)(F)c1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnnc(c1)N1CCC1
Show InChI InChI=1S/C20H20ClF3N4O/c21-15-4-5-16(17(10-15)20(22,23)24)13-3-1-6-28(12-13)19(29)14-9-18(26-25-11-14)27-7-2-8-27/h4-5,9-11,13H,1-3,6-8,12H2
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 730n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...

US Patent US9790201 (2017)


BindingDB Entry DOI: 10.7270/Q2377BVZ
More data for this
Ligand-Target Pair