BDBM347601 5-{[3-(2-Methoxyphenyl)piperidin-1-yl]carbonyl}-N-methylpyridazin-3-amine::US9790201, 86

SMILES: CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccccc1OC

InChI Key: InChIKey=ORVJIHUFJITNOL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347601 (5-{[3-(2-Methoxyphenyl)piperidin-1-yl]carbonyl}-N-...) Show SMILES CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccccc1OC Show InChI InChI=1S/C18H22N4O2/c1-19-17-10-14(11-20-21-17)18(23)22-9-5-6-13(12-22)15-7-3-4-8-16(15)24-2/h3-4,7-8,10-11,13H,5-6,9,12H2,1-2H3,(H,19,21)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair