BDBM347605 3-(4-Chlorophenyl)-1-[(1-ethyl-1H-pyrazol-4-yl)carbonyl]piperidine::US9790201, 90

SMILES: CCn1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1

InChI Key: InChIKey=XTEITOULAVWRAG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347605 (3-(4-Chlorophenyl)-1-[(1-ethyl-1H-pyrazol-4-yl)car...) Show SMILES CCn1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H20ClN3O/c1-2-21-12-15(10-19-21)17(22)20-9-3-4-14(11-20)13-5-7-16(18)8-6-13/h5-8,10,12,14H,2-4,9,11H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair