BDBM347697 (E)-1-(2-Chlorophenyl)-2-[(6- chloro-3-pyridyl)oxy]-3- (dimethylamino)prop-2-en-1-one::US9790217, 19

SMILES: CN(C)\C=C(\Oc1ccc(Cl)nc1)C(=O)c1ccccc1Cl

InChI Key: InChIKey=DKSBPSFRMXMCGH-GXDHUFHOSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM347697 ((E)-1-(2-Chlorophenyl)-2-[(6- chloro-3-pyridyl)oxy...) Show SMILES CN(C)\C=C(\Oc1ccc(Cl)nc1)C(=O)c1ccccc1Cl Show InChI InChI=1S/C16H14Cl2N2O2/c1-20(2)10-14(22-11-7-8-15(18)19-9-11)16(21)12-5-3-4-6-13(12)17/h3-10H,1-2H3/b14-10+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.387	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM347697 ((E)-1-(2-Chlorophenyl)-2-[(6- chloro-3-pyridyl)oxy...) Show SMILES CN(C)\C=C(\Oc1ccc(Cl)nc1)C(=O)c1ccccc1Cl Show InChI InChI=1S/C16H14Cl2N2O2/c1-20(2)10-14(22-11-7-8-15(18)19-9-11)16(21)12-5-3-4-6-13(12)17/h3-10H,1-2H3/b14-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.113	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair