null

SMILES: CN(C)C(=C\OC1(CC=CC=C1)C#N)\C(=O)c1cccc(F)c1F

InChI Key: InChIKey=ZILLCXHICUQIMU-RVDMUPIBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM347706 ((E)-1-[(2,3-Difluorobenzoyl)-2-(dimethylamino)viny...) Show SMILES CN(C)C(=C\OC1(CC=CC=C1)C#N)\C(=O)c1cccc(F)c1F |c:8,10| Show InChI InChI=1S/C18H16F2N2O2/c1-22(2)15(11-24-18(12-21)9-4-3-5-10-18)17(23)13-7-6-8-14(19)16(13)20/h3-9,11H,10H2,1-2H3/b15-11+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.161	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM347706 ((E)-1-[(2,3-Difluorobenzoyl)-2-(dimethylamino)viny...) Show SMILES CN(C)C(=C\OC1(CC=CC=C1)C#N)\C(=O)c1cccc(F)c1F |c:8,10| Show InChI InChI=1S/C18H16F2N2O2/c1-22(2)15(11-24-18(12-21)9-4-3-5-10-18)17(23)13-7-6-8-14(19)16(13)20/h3-9,11H,10H2,1-2H3/b15-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00700	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair