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SMILES: CCc1cnc(nc1NCc1ccc(cc1)-c1ccccc1)-c1ccccc1C(C)C

InChI Key: InChIKey=HHMGGJHFUODDEW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350387   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM350387
PNG
(US9802904, 60)
Show SMILES CCc1cnc(nc1NCc1ccc(cc1)-c1ccccc1)-c1ccccc1C(C)C
Show InChI InChI=1S/C28H29N3/c1-4-22-19-30-28(26-13-9-8-12-25(26)20(2)3)31-27(22)29-18-21-14-16-24(17-15-21)23-10-6-5-7-11-23/h5-17,19-20H,4,18H2,1-3H3,(H,29,30,31)
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US Patent
n/an/a 43n/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware

US Patent


Assay Description
This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...

US Patent US9802904 (2017)


BindingDB Entry DOI: 10.7270/Q2TF00H8
More data for this
Ligand-Target Pair