BDBM350904 3-Phenyl-2-(4-pyridylmethylthio)-4-oxo-3,4-dihydroquinazoline::US9796687, Compound 27

SMILES: O=c1n(c(SCc2ccncc2)nc2ccccc12)-c1ccccc1

InChI Key: InChIKey=WVIORRIIXYVEIF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM350904 (3-Phenyl-2-(4-pyridylmethylthio)-4-oxo-3,4-dihydro...) Show SMILES O=c1n(c(SCc2ccncc2)nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C20H15N3OS/c24-19-17-8-4-5-9-18(17)22-20(23(19)16-6-2-1-3-7-16)25-14-15-10-12-21-13-11-15/h1-13H,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS US Patent					Assay Description Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...				US Patent US9796687 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MDC
					More data for this Ligand-Target Pair