BDBM351411 1,4:3,6-dianhydro-5-O-[4-[(3-bromo-4- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro- D-iditol::US9796704, Entry 131

SMILES: COc1cc2c(Nc3ccc(C)c(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12

InChI Key: InChIKey=PFBDUGXDPNHKAM-IDCXYZFESA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 351411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM351411 (1,4:3,6-dianhydro-5-O-[4-[(3-bromo-4- methylphenyl...) Show SMILES COc1cc2c(Nc3ccc(C)c(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C22H21BrFN3O4/c1-11-3-4-12(5-14(11)23)27-22-13-6-17(28-2)18(7-16(13)25-10-26-22)31-19-9-30-20-15(24)8-29-21(19)20/h3-7,10,15,19-21H,8-9H2,1-2H3,(H,25,26,27)/t15-,19-,20+,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM351411 (1,4:3,6-dianhydro-5-O-[4-[(3-bromo-4- methylphenyl...) Show SMILES COc1cc2c(Nc3ccc(C)c(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C22H21BrFN3O4/c1-11-3-4-12(5-14(11)23)27-22-13-6-17(28-2)18(7-16(13)25-10-26-22)31-19-9-30-20-15(24)8-29-21(19)20/h3-7,10,15,19-21H,8-9H2,1-2H3,(H,25,26,27)/t15-,19-,20+,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM351411 (1,4:3,6-dianhydro-5-O-[4-[(3-bromo-4- methylphenyl...) Show SMILES COc1cc2c(Nc3ccc(C)c(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C22H21BrFN3O4/c1-11-3-4-12(5-14(11)23)27-22-13-6-17(28-2)18(7-16(13)25-10-26-22)31-19-9-30-20-15(24)8-29-21(19)20/h3-7,10,15,19-21H,8-9H2,1-2H3,(H,25,26,27)/t15-,19-,20+,21+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM351411 (1,4:3,6-dianhydro-5-O-[4-[(3-bromo-4- methylphenyl...) Show SMILES COc1cc2c(Nc3ccc(C)c(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C22H21BrFN3O4/c1-11-3-4-12(5-14(11)23)27-22-13-6-17(28-2)18(7-16(13)25-10-26-22)31-19-9-30-20-15(24)8-29-21(19)20/h3-7,10,15,19-21H,8-9H2,1-2H3,(H,25,26,27)/t15-,19-,20+,21+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair