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SMILES: COc1cc(cc(OC)c1OC)-c1cnc2ncn(-c3ccc4[nH]ccc4c3)c2n1

InChI Key: InChIKey=OFDLUROFHFYRIA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354849 (US10485800, Example 126 | US9814704, Example 126) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2ncn(-c3ccc4[nH]ccc4c3)c2n1 Show InChI InChI=1S/C22H19N5O3/c1-28-18-9-14(10-19(29-2)20(18)30-3)17-11-24-21-22(26-17)27(12-25-21)15-4-5-16-13(8-15)6-7-23-16/h4-12,23H,1-3H3	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354849 (US10485800, Example 126 | US9814704, Example 126) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2ncn(-c3ccc4[nH]ccc4c3)c2n1 Show InChI InChI=1S/C22H19N5O3/c1-28-18-9-14(10-19(29-2)20(18)30-3)17-11-24-21-22(26-17)27(12-25-21)15-4-5-16-13(8-15)6-7-23-16/h4-12,23H,1-3H3	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair