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SMILES: O=C1CN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CCN1

InChI Key: InChIKey=SCKAXKGFVSWWNS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354865 (Preparation of 4-{4-[3-(1H-indol-5-yl)-1H-pyrrolo[...) Show SMILES O=C1CN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CCN1 Show InChI InChI=1S/C26H23N5O/c32-25-16-31(10-9-28-25)15-17-1-3-18(4-2-17)21-12-22-23(14-30-26(22)29-13-21)19-5-6-24-20(11-19)7-8-27-24/h1-8,11-14,27H,9-10,15-16H2,(H,28,32)(H,29,30)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354865 (Preparation of 4-{4-[3-(1H-indol-5-yl)-1H-pyrrolo[...) Show SMILES O=C1CN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CCN1 Show InChI InChI=1S/C26H23N5O/c32-25-16-31(10-9-28-25)15-17-1-3-18(4-2-17)21-12-22-23(14-30-26(22)29-13-21)19-5-6-24-20(11-19)7-8-27-24/h1-8,11-14,27H,9-10,15-16H2,(H,28,32)(H,29,30)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair