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SMILES: C[C@@](O)(CN1CC[C@H](F)C1=O)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=FJVWQOQSMAKEAY-OXJNMPFZSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356948   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Period circadian protein homolog 2


(Homo sapiens (Human))
BDBM356948
PNG
((S)-1-((S)-3-(9H- carbazol-9-yl)-2- hydroxy-2- met...)
Show SMILES C[C@@](O)(CN1CC[C@H](F)C1=O)Cn1c2ccccc2c2ccccc12 |r|
Show InChI InChI=1S/C20H21FN2O2/c1-20(25,12-22-11-10-16(21)19(22)24)13-23-17-8-4-2-6-14(17)15-7-3-5-9-18(15)23/h2-9,16,25H,10-13H2,1H3/t16-,20+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 309n/an/an/an/a



Synchronicity Pharma, Inc.

US Patent


Assay Description
In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...


US Patent US10759777 (2020)

More data for this
Ligand-Target Pair
Period circadian protein homolog 2


(Homo sapiens (Human))
BDBM356948
PNG
((S)-1-((S)-3-(9H- carbazol-9-yl)-2- hydroxy-2- met...)
Show SMILES C[C@@](O)(CN1CC[C@H](F)C1=O)Cn1c2ccccc2c2ccccc12 |r|
Show InChI InChI=1S/C20H21FN2O2/c1-20(25,12-22-11-10-16(21)19(22)24)13-23-17-8-4-2-6-14(17)15-7-3-5-9-18(15)23/h2-9,16,25H,10-13H2,1H3/t16-,20+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 309n/an/an/an/a



Reset Therapeutics, Inc.

US Patent


Assay Description
Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...


US Patent US10214507 (2019)


BindingDB Entry DOI: 10.7270/Q2KH0QMT
More data for this
Ligand-Target Pair