BDBM35696 5H-1-benzazepin-5-ylidene acetamide, 10c
SMILES: CCc1ccn(n1)-c1ccc(C(=O)N2CCC(F)(F)\C(=C/C(=O)NCc3ccccn3)c3ccccc23)c(Cl)c1
InChI Key: InChIKey=KYSQENAKPIHTQX-BWAHOGKJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35696![]() (5H-1-benzazepin-5-ylidene acetamide, 10c) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 21 | -10.4 | n/a | n/a | >1.00E+4 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair |