BDBM357863 US10214536, Compound 19

SMILES: Nc1nc2oc3ccc(cc3c(=O)c2cc1C(O)=O)C1CCCCCC1

InChI Key: InChIKey=FKOSZOLEWMIKNF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein cereblon/Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM357863 (US10214536, Compound 19) Show SMILES Nc1nc2oc3ccc(cc3c(=O)c2cc1C(O)=O)C1CCCCCC1 Show InChI InChI=1S/C20H20N2O4/c21-18-15(20(24)25)10-14-17(23)13-9-12(11-5-3-1-2-4-6-11)7-8-16(13)26-19(14)22-18/h7-11H,1-6H2,(H2,21,22)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...				US Patent US10214536 (2019) BindingDB Entry DOI: 10.7270/Q2N87D2S
					More data for this Ligand-Target Pair