BDBM357879 US10214536, Compound 55b

SMILES: Nc1nc2oc3ccc(\C=C\C4CC4)cc3c(=O)c2cc1C(O)=O

InChI Key: InChIKey=FJTZYRWIDJILFS-ONEGZZNKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357879   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein cereblon/Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM357879 (US10214536, Compound 55b) Show SMILES Nc1nc2oc3ccc(\C=C\C4CC4)cc3c(=O)c2cc1C(O)=O Show InChI InChI=1S/C18H14N2O4/c19-16-13(18(22)23)8-12-15(21)11-7-10(4-3-9-1-2-9)5-6-14(11)24-17(12)20-16/h3-9H,1-2H2,(H2,19,20)(H,22,23)/b4-3+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...				US Patent US10214536 (2019) BindingDB Entry DOI: 10.7270/Q2N87D2S
					More data for this Ligand-Target Pair