BDBM359105 US10220048, Compound AA15::US10952992, No. AA15

SMILES: COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1nc(CC(F)(F)F)cs1

InChI Key: InChIKey=UEDXDGTYRBGQSC-PMACEKPBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 359105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein phosphatase beta (PTPβ) (Homo sapiens (Human))	BDBM359105 (US10220048, Compound AA15 | US10952992, No. AA15) Show SMILES COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1nc(CC(F)(F)F)cs1 |r| Show InChI InChI=1S/C24H25F3N4O6S2/c1-37-23(33)30-19(11-15-5-3-2-4-6-15)21(32)29-20(22-28-18(14-38-22)13-24(25,26)27)12-16-7-9-17(10-8-16)31-39(34,35)36/h2-10,14,19-20,31H,11-13H2,1H3,(H,29,32)(H,30,33)(H,34,35,36)/t19-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
AERPIO PHARMACEUTICALS, INC. US Patent					Assay Description Non-limiting examples of the HPTP-β IC50 (μM) activity.				US Patent US10952992 (2021)
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (PTPβ) (Homo sapiens (Human))	BDBM359105 (US10220048, Compound AA15 | US10952992, No. AA15) Show SMILES COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1nc(CC(F)(F)F)cs1 |r| Show InChI InChI=1S/C24H25F3N4O6S2/c1-37-23(33)30-19(11-15-5-3-2-4-6-15)21(32)29-20(22-28-18(14-38-22)13-24(25,26)27)12-16-7-9-17(10-8-16)31-39(34,35)36/h2-10,14,19-20,31H,11-13H2,1H3,(H,29,32)(H,30,33)(H,34,35,36)/t19-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
AERPIO THERAPEUTICS, INC. US Patent					Assay Description HPTP-β inhibition can be tested by any method chosen by the formulator, for example, Amarasinge K. K. et al., “Design and Synthesis of Potent, N...				US Patent US10220048 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VC9
					More data for this Ligand-Target Pair