BDBM359473 US10221129, Example BB-29

SMILES: CN(C)C(=O)C1Cc2cccnc2N1S(=O)(=O)NC(=O)N[C@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc2scnc2c1

InChI Key: InChIKey=DELVNTYXEVIFPU-WTQRLHSKSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Envelope glycoprotein gp160 (Human immunodeficiency virus type 1 (isolate BRU/L...)	BDBM359473 (US10221129, Example BB-29) Show SMILES CN(C)C(=O)C1Cc2cccnc2N1S(=O)(=O)NC(=O)N[C@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc2scnc2c1 |r| Show InChI InChI=1S/C28H27F2N7O5S2/c1-35(2)27(39)23-12-17-5-4-8-31-25(17)37(23)44(41,42)34-28(40)33-22(11-16-9-18(29)13-19(30)10-16)26(38)36(3)20-6-7-24-21(14-20)32-15-43-24/h4-10,13-15,22-23H,11-12H2,1-3H3,(H2,33,34,40)/t22-,23?/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a
VIIV HEALTHCARE UK (NO.5) LIMITED US Patent					Assay Description HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...				US Patent US10221129 (2019) BindingDB Entry DOI: 10.7270/Q2R213N8
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