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SMILES: CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F

InChI Key: InChIKey=FINQXXLEXPYMQY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 359720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359720 (US10435355, Example 4 | US9822068, 4 | [4-fluoro-3...) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C20H21FN2O3/c1-22-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)21)26-20(25)23-15-7-2-3-8-15/h4-6,9-12,15H,2-3,7-8H2,1H3,(H,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM359720 (US10435355, Example 4 | US9822068, 4 | [4-fluoro-3...) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C20H21FN2O3/c1-22-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)21)26-20(25)23-15-7-2-3-8-15/h4-6,9-12,15H,2-3,7-8H2,1H3,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359720 (US10435355, Example 4 | US9822068, 4 | [4-fluoro-3...) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C20H21FN2O3/c1-22-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)21)26-20(25)23-15-7-2-3-8-15/h4-6,9-12,15H,2-3,7-8H2,1H3,(H,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM359720 (US10435355, Example 4 | US9822068, 4 | [4-fluoro-3...) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C20H21FN2O3/c1-22-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)21)26-20(25)23-15-7-2-3-8-15/h4-6,9-12,15H,2-3,7-8H2,1H3,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair