BDBM361938 9-ethyl-N-[(1S)-1-{[3-(1- methylethyl)morpholin-4- yl]carbonyl}propyl]-8-(2- methylpyrimidin-5-yl)-9H-purin- 6-amine::US10221178, Compound 2-32

SMILES: CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1CCOCC1C(C)C

InChI Key: InChIKey=DHTXUSOUOBNCBY-ZENAZSQFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM361938 (9-ethyl-N-[(1S)-1-{[3-(1- methylethyl)morpholin-4-...) Show SMILES CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1CCOCC1C(C)C |r| Show InChI InChI=1S/C23H32N8O2/c1-6-17(23(32)31-8-9-33-12-18(31)14(3)4)28-20-19-22(27-13-26-20)30(7-2)21(29-19)16-10-24-15(5)25-11-16/h10-11,13-14,17-18H,6-9,12H2,1-5H3,(H,26,27,28)/t17-,18?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...				US Patent US10221178 (2019) BindingDB Entry DOI: 10.7270/Q20C4Z2D
					More data for this Ligand-Target Pair