BDBM361972 N-{(R or S)-1-cyclopropyl-2- [(cis)-2,6-dimethylmorpholin-4- yl]-2-oxoethyl}-3-ethyl-2-(2- methylpyrimidin-5-yl)-3H- imidazo[4,5-b]pyridin-7-amine::US10221178, Compound 3-4

SMILES: CCn1c(nc2c(NC(C3CC3)C(=O)N3C[C@H](C)O[C@H](C)C3)ccnc12)-c1cnc(C)nc1

InChI Key: InChIKey=HGIVXNLUGRVOJM-DBIVSCPCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM361972 (N-{(R or S)-1-cyclopropyl-2- [(cis)-2,6-dimethylmo...) Show SMILES CCn1c(nc2c(NC(C3CC3)C(=O)N3C[C@H](C)O[C@H](C)C3)ccnc12)-c1cnc(C)nc1 |r| Show InChI InChI=1S/C24H31N7O2/c1-5-31-22(18-10-26-16(4)27-11-18)29-21-19(8-9-25-23(21)31)28-20(17-6-7-17)24(32)30-12-14(2)33-15(3)13-30/h8-11,14-15,17,20H,5-7,12-13H2,1-4H3,(H,25,28)/t14-,15+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...				US Patent US10221178 (2019) BindingDB Entry DOI: 10.7270/Q20C4Z2D
					More data for this Ligand-Target Pair