null

SMILES: COc1cncc(c1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12

InChI Key: InChIKey=GVQUTCQPZXNVNN-CPJSRVTESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362698 (US9840498, 25) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-23(13-31)27(36-30(32)34-17)37-16-20(39)12-25(37)28-35-24-10-6-9-22(18-11-21(41-2)15-33-14-18)26(24)29(40)38(28)19-7-4-3-5-8-19/h3-11,14-15,20,25,39H,12,16H2,1-2H3,(H2,32,34,36)/t20-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362698 (US9840498, 25) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-23(13-31)27(36-30(32)34-17)37-16-20(39)12-25(37)28-35-24-10-6-9-22(18-11-21(41-2)15-33-14-18)26(24)29(40)38(28)19-7-4-3-5-8-19/h3-11,14-15,20,25,39H,12,16H2,1-2H3,(H2,32,34,36)/t20-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362698 (US9840498, 25) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-23(13-31)27(36-30(32)34-17)37-16-20(39)12-25(37)28-35-24-10-6-9-22(18-11-21(41-2)15-33-14-18)26(24)29(40)38(28)19-7-4-3-5-8-19/h3-11,14-15,20,25,39H,12,16H2,1-2H3,(H2,32,34,36)/t20-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair