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SMILES: CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3C(C(C)C)N(Cc4ccc(cc4)C(F)(F)F)C(=O)c3c2)nc1

InChI Key: InChIKey=UNTKNNKVFSQMGN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362918   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM362918
PNG
(US9845308, Example 27)
Show SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3C(C(C)C)N(Cc4ccc(cc4)C(F)(F)F)C(=O)c3c2)nc1
Show InChI InChI=1S/C28H28F3N3O4S/c1-4-39(37,38)22-11-10-21(32-15-22)14-33-26(35)19-7-12-23-24(13-19)27(36)34(25(23)17(2)3)16-18-5-8-20(9-6-18)28(29,30)31/h5-13,15,17,25H,4,14,16H2,1-3H3,(H,33,35)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
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UniChem
US Patent
<100n/an/an/an/an/an/an/an/a



Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...

US Patent US9845308 (2017)


BindingDB Entry DOI: 10.7270/Q2DF6TG9
More data for this
Ligand-Target Pair