BDBM362935 5-Chloro-2-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclopentyl]oxy}-N-(1,3-thiazol-4-yl)benzenesulfonamide Na Salt::US9845313, Example 11
SMILES: Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)N([Na])c1cscn1
InChI Key: InChIKey=QWEDICCSKYIBAI-BTAXJDQBSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM362935 (5-Chloro-2-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyr...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
DAIICHI SANKYO COMPANY, LIMITED US Patent | Assay Description Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The... | US Patent US9845313 (2017) BindingDB Entry DOI: 10.7270/Q25141H5 | |||||||||||
More data for this Ligand-Target Pair |