BDBM36373 (5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-6,7,8-triol. 1a::CID10013016

SMILES: OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12

InChI Key: InChIKey=RZRDQZQPTISYKY-JWXFUTCRSA-N

Data: 17 KI

PDB links: 12 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 36373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3965 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3130 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Beta-mannosidase (Bacteroides thetaiotaomicron)	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.40E+3	-8.30	n/a	n/a	n/a	n/a	n/a	5.6	37
The Medical School, Newcastle University					Assay Description Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.				Nat Chem Biol 4: 306-12 (2008) Article DOI: 10.1038/nchembio.81 BindingDB Entry DOI: 10.7270/Q2X34VS6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3994 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3991 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2948 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3990 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	2.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3858 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3962 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4073 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
GH92 alpha-mannosidase (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 1032 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	7.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3963 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	8.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4093 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.60E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4092 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.80E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 1878 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair
Alpha-1,2-mannosidase, putative (Bacteroides thetaiotaomicron )	BDBM36373 ((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12 Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	5.80E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3784 assessed as reduction of mannose release using 4NP-mannopyranoside substrate				Nat Chem Biol 6: 125-32 (2010) Article DOI: 10.1038/nchembio.278 BindingDB Entry DOI: 10.7270/Q2ZW1PQB
					More data for this Ligand-Target Pair