BDBM36640 CHEMBL26514::L-159,061
SMILES: CCCCc1nc2ccc(O)cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InChI Key: InChIKey=UNVNHFHIKCWHHG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Metallo-beta-lactamase (Bacteroides fragilis) | BDBM36640 (CHEMBL26514 | L-159,061) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.0 | 37 |
Merck Research Laboratories | Assay Description Enzyme inhibition assay by biphenyl tetrazoles (BPTS)using metallo-beta-lactamase. | Chem Biol 5: 185-96 (1998) Article DOI: 10.1016/s1074-5521(98)90632-9 BindingDB Entry DOI: 10.7270/Q20R9MSC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin II type 1a (AT-1a) receptor (RABBIT) | BDBM36640 (CHEMBL26514 | L-159,061) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Ability to displace [125I]-Sar1-Ile8-AII from angiotensin II receptor, type 1 in rabbit aorta in presence of 0.2% bovine serum albumin (BSA) was dete... | Bioorg Med Chem Lett 3: 1299-1304 (1993) Article DOI: 10.1016/S0960-894X(00)80335-2 BindingDB Entry DOI: 10.7270/Q29P31KG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dehydropeptidase-I (DHP-1) (Homo sapiens (Human)) | BDBM36640 (CHEMBL26514 | L-159,061) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 37 |
Merck Research Laboratories | Assay Description Enzyme inhibition assay by biphenyl tetrazoles (BPTS)using dehydropeptidase 1 (DPH-1). | Chem Biol 5: 185-96 (1998) Article DOI: 10.1016/s1074-5521(98)90632-9 BindingDB Entry DOI: 10.7270/Q20R9MSC | |||||||||||
More data for this Ligand-Target Pair |