BDBM367200 7-methyl-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide::US10226452, Example 18

SMILES: Cc1cccc2n(C(=O)NCCCCc3ccccc3)c(=O)oc12

InChI Key: InChIKey=AXDCZLBKICDYMS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid ceramidase (Homo sapiens (Human))	BDBM367200 (7-methyl-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole...) Show SMILES Cc1cccc2n(C(=O)NCCCCc3ccccc3)c(=O)oc12 Show InChI InChI=1S/C19H20N2O3/c1-14-8-7-12-16-17(14)24-19(23)21(16)18(22)20-13-6-5-11-15-9-3-2-4-10-15/h2-4,7-10,12H,5-6,11,13H2,1H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of recombinant human acid ceramidase expressed in HEK293 cells using N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)-4-(2-oxochromen-7-yl)-oxybutyl...				J Med Chem 58: 9258-72 (2015) Article DOI: 10.1021/acs.jmedchem.5b01188 BindingDB Entry DOI: 10.7270/Q2CF9T36
					More data for this Ligand-Target Pair
Acid ceramidase (Homo sapiens (Human))	BDBM367200 (7-methyl-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole...) Show SMILES Cc1cccc2n(C(=O)NCCCCc3ccccc3)c(=O)oc12 Show InChI InChI=1S/C19H20N2O3/c1-14-8-7-12-16-17(14)24-19(23)21(16)18(22)20-13-6-5-11-15-9-3-2-4-10-15/h2-4,7-10,12H,5-6,11,13H2,1H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec					Assay Description The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...				J Med Chem 50: 2767-78 (2007) BindingDB Entry DOI: 10.7270/Q23T9KH0
					More data for this Ligand-Target Pair