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SMILES: COc1ccc(CNc2nc(nc3N(CNc23)C(C)C)N2CCCCCC2)cc1

InChI Key: InChIKey=IEYREEZIBXSKBH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 36745   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 1


(Homo sapiens (Human))		BDBM36745
PNG
(6-(4-methoxybenzylamino) core C2-substituent, 38)
Show SMILES COc1ccc(CNc2nc(nc3N(CNc23)C(C)C)N2CCCCCC2)cc1
Show InChI InChI=1S/C22H32N6O/c1-16(2)28-15-24-19-20(23-14-17-8-10-18(29-3)11-9-17)25-22(26-21(19)28)27-12-6-4-5-7-13-27/h8-11,16,24H,4-7,12-15H2,1-3H3,(H,23,25,26)
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Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



University of California, Berkeley



Assay Description
Inhibition assay using CDK1/cyclin B.

Chem Biol 6: 361-75 (1999)


Article DOI: 10.1016/S1074-5521(99)80048-9
BindingDB Entry DOI: 10.7270/Q2HM56TM
More data for this
Ligand-Target Pair