null

SMILES: CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1

InChI Key: InChIKey=MPRDYIJNNULDAX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368327 (US10227338, Example 114 | US10227338, Example 116) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C19H21ClFN5O2S2/c1-22-7-9-26(2)17-6-4-3-5-15(17)24-16-12-14(21)18(11-13(16)20)30(27,28)25-19-23-8-10-29-19/h3-6,8,10-12,22,24H,7,9H2,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368327 (US10227338, Example 114 | US10227338, Example 116) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C19H21ClFN5O2S2/c1-22-7-9-26(2)17-6-4-3-5-15(17)24-16-12-14(21)18(11-13(16)20)30(27,28)25-19-23-8-10-29-19/h3-6,8,10-12,22,24H,7,9H2,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair