null

SMILES: CC(C)OC[N]1=CN(Cc2cnn(C)c2)C(=O)c2cc(ccc12)S(=O)(=O)NC1(C)CC1

InChI Key: InChIKey=CEJCRJXUINANRP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 371186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM371186 (US10239843, Example 293) Show SMILES CC(C)OC[N]1=CN(Cc2cnn(C)c2)C(=O)c2cc(ccc12)S(=O)(=O)NC1(C)CC1 |t:5| Show InChI InChI=1S/C21H28N5O4S/c1-15(2)30-14-26-13-25(12-16-10-22-24(4)11-16)20(27)18-9-17(5-6-19(18)26)31(28,29)23-21(3)7-8-21/h5-6,9-11,13,15,23H,7-8,12,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanita					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				J Med Chem 51: 1058-62 (2008) BindingDB Entry DOI: 10.7270/Q21R6SSM
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM371186 (US10239843, Example 293) Show SMILES CC(C)OC[N]1=CN(Cc2cnn(C)c2)C(=O)c2cc(ccc12)S(=O)(=O)NC1(C)CC1 |t:5| Show InChI InChI=1S/C21H28N5O4S/c1-15(2)30-14-26-13-25(12-16-10-22-24(4)11-16)20(27)18-9-17(5-6-19(18)26)31(28,29)23-21(3)7-8-21/h5-6,9-11,13,15,23H,7-8,12,14H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanita					Assay Description PARP1 In vitro selectivity assays were conducted as a 10 ul reaction volume in a NUNC Maxisorp 384-well assay plate pre-coated in-house with Histones...				J Med Chem 51: 1058-62 (2008) BindingDB Entry DOI: 10.7270/Q21R6SSM
					More data for this Ligand-Target Pair
ADP-ribosylhydrolase ARH3 (Homo sapiens (Human))	BDBM371186 (US10239843, Example 293) Show SMILES CC(C)OC[N]1=CN(Cc2cnn(C)c2)C(=O)c2cc(ccc12)S(=O)(=O)NC1(C)CC1 |t:5| Show InChI InChI=1S/C21H28N5O4S/c1-15(2)30-14-26-13-25(12-16-10-22-24(4)11-16)20(27)18-9-17(5-6-19(18)26)31(28,29)23-21(3)7-8-21/h5-6,9-11,13,15,23H,7-8,12,14H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanita					Assay Description ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...				J Med Chem 51: 1058-62 (2008) BindingDB Entry DOI: 10.7270/Q21R6SSM
					More data for this Ligand-Target Pair