BindingDB logo
myBDB logout

null

SMILES: COc1cc(Cn2ncc(NC(=O)Cc3ccc(OC4CC(F)(F)C4)cc3)n2)cc(F)c1F

InChI Key: InChIKey=KIHNMXQBTVVOHM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372676   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM372676
PNG
(2-[4-(3,3-Difluoro-cyclobutoxy)-phenyl]-N-[2-(3,4-...)
Show SMILES COc1cc(Cn2ncc(NC(=O)Cc3ccc(OC4CC(F)(F)C4)cc3)n2)cc(F)c1F
Show InChI InChI=1S/C22H20F4N4O3/c1-32-18-7-14(6-17(23)21(18)24)12-30-27-11-19(29-30)28-20(31)8-13-2-4-15(5-3-13)33-16-9-22(25,26)10-16/h2-7,11,16H,8-10,12H2,1H3,(H,28,29,31)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 350n/an/an/an/an/an/a



University of Alberta



Assay Description
Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...

J Med Chem 49: 1668-83 (2006)


BindingDB Entry DOI: 10.7270/Q2794709
More data for this
Ligand-Target Pair