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SMILES: CC(=O)N1CCN(CC1)c1ccc(NC(=O)Cc2ccc(cc2)-c2ccnc(Cl)c2)nc1

InChI Key: InChIKey=IVVKERSPSXZXBI-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374980   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Wnt-3a


(Homo sapiens (Human))		BDBM374980
PNG
(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(4-(2...)
Show SMILES CC(=O)N1CCN(CC1)c1ccc(NC(=O)Cc2ccc(cc2)-c2ccnc(Cl)c2)nc1
Show InChI InChI=1S/C24H24ClN5O2/c1-17(31)29-10-12-30(13-11-29)21-6-7-23(27-16-21)28-24(32)14-18-2-4-19(5-3-18)20-8-9-26-22(25)15-20/h2-9,15-16H,10-14H2,1H3,(H,27,28,32)
PDB

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KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 0.200n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...

J Med Chem 50: 5727-34 (2007)


BindingDB Entry DOI: 10.7270/Q2GM89KJ
More data for this
Ligand-Target Pair