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SMILES: Cc1cc(OC(=O)N2CCCCC2)ccc1NC(=O)c1nn(N2CC=CN(C2)C(=O)C=C)c2ncnc(N)c12

InChI Key: InChIKey=WLUQXMUQTUSNQU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376982   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor tyrosine-protein kinase erbB-2


(Homo sapiens (Human))		BDBM376982
PNG
(US9920060, 70)
Show SMILES Cc1cc(OC(=O)N2CCCCC2)ccc1NC(=O)c1nn(N2CC=CN(C2)C(=O)C=C)c2ncnc(N)c12 |c:26|
Show InChI InChI=1S/C26H29N9O4/c1-3-20(36)33-12-7-13-34(16-33)35-24-21(23(27)28-15-29-24)22(31-35)25(37)30-19-9-8-18(14-17(19)2)39-26(38)32-10-5-4-6-11-32/h3,7-9,12,14-15H,1,4-6,10-11,13,16H2,2H3,(H,30,37)(H2,27,28,29)
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MMDB

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PC cid
PC sid
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US Patent
n/an/a 10n/an/an/an/an/an/a



Universite Paris 7-Denis Diderot



Assay Description
For the inhibitory activity measurement of each compound, the compound of the present invention or staurosporine was first serially diluted with dime...

Bioorg Med Chem 16: 1242-53 (2008)


BindingDB Entry DOI: 10.7270/Q2BR8VHD
More data for this
Ligand-Target Pair