BDBM377190 N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-dihydrofuro[2,3-b]pyridin-5-yl}-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide::US10265307, Example 39::US10517858, Example 39::US10828290, Example 39

SMILES: C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F

InChI Key: InChIKey=CXVCGOXRMUMGCU-KGLIPLIRSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 377190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 49: 4116-26 (2006) BindingDB Entry DOI: 10.7270/Q2FJ2K39
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 49: 4116-26 (2006) BindingDB Entry DOI: 10.7270/Q2FJ2K39
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 49: 4116-26 (2006) BindingDB Entry DOI: 10.7270/Q2FJ2K39
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.84 compound/DMSO in the assay buffer (...				US Patent US10517858 (2019) BindingDB Entry DOI: 10.7270/Q2XD1422
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description Pim-2 kinase assay-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay buffer (50 m...				US Patent US10517858 (2019) BindingDB Entry DOI: 10.7270/Q2XD1422
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	US11229631, Example 39 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...				US Patent US10828290 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...				US Patent US10828290 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...				US Patent US10828290 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PIM (Homo sapiens (Human))	US11229631, Example 39 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PIM (Homo sapiens (Human))	US11229631, Example 39 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM377190 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-2,3-...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1c2CCOc2ncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F |r,wU:3.3,1.0,(-.15,2.69,;-1.48,1.93,;-2.82,2.69,;-4.15,1.93,;-5.48,2.69,;-4.15,.38,;-2.82,-.38,;-1.48,.38,;-2.82,-1.93,;-4.15,-2.69,;-5.61,-2.22,;-6.52,-3.47,;-5.61,-4.71,;-4.15,-4.23,;-2.82,-5,;-1.48,-4.23,;-1.48,-2.69,;-.15,-1.93,;1.18,-2.69,;1.18,-4.23,;2.52,-1.93,;3.85,-2.69,;5.19,-1.93,;5.19,-.38,;6.52,.38,;3.85,.38,;2.52,-.38,;3.85,1.93,;2.52,2.7,;1.18,1.93,;2.52,4.24,;3.85,5,;5.19,4.24,;5.19,2.7,;6.52,1.93,)| Show InChI InChI=1S/C25H24F3N5O2/c1-13-9-14(29)12-33(11-13)23-15-7-8-35-25(15)30-10-20(23)32-24(34)19-6-5-18(28)22(31-19)21-16(26)3-2-4-17(21)27/h2-6,10,13-14H,7-9,11-12,29H2,1H3,(H,32,34)/t13-,14+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.84 compound/DMSO in the assay buffer (...				US Patent US10517858 (2019) BindingDB Entry DOI: 10.7270/Q2XD1422
					More data for this Ligand-Target Pair